Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)Alejandro J. Cagnoni, Oscar Varela, María Laura Uhrig and José Kovensky European Journal of Organic Chemistry Volume 2013, Issue 5, pages 972–983, February 2013 Article first published online: 13 DEC 2012 | DOI: 10.1002/ejoc.201201412 http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201201412/abstract Ruthenium-catalyzed cycloaddition of… Continue reading Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)
Tag: SYNTHESIS
Immunosuppressant Drug Rapamycin Helps Preserving Female Fertility
Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidneytransplants. It prevents activation of T cells and B cells by inhibiting their response tointerleukin-2 (IL-2). A macrolide, sirolimus was discovered by Brazilian researchers as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island[1] — an island also known as Rapa Nui.[2] It was approved by the… Continue reading Immunosuppressant Drug Rapamycin Helps Preserving Female Fertility
(Z)-5-tetradecen-1-ol, Potential female sex attractant
Follow my blog with Bloglovin (Z)-5-Tetradecen-1-ol, mw 212.37, formula C14H20O CAS 40642-42-0 Odorant receptors, present on nasal sensory neurons, perceive volatile compounds and regulate animal behavior such as reproduction. The nature of the ligands interacting with these receptors is, however, largely unknown. Keiichi Yoshikawa and colleagues, University of Tokyo, Japan, shed new light on this… Continue reading (Z)-5-tetradecen-1-ol, Potential female sex attractant
Facile Synthesis of Benzaldehyde-Functionalized Ionic Liquids and Their Flexible Functional Group Transformations
Facile Synthesis of Benzaldehyde-Functionalized Ionic Liquids and Their Flexible Functional Group Transformations http://www.hindawi.com/journals/oci/2012/208128/ Organic Chemistry International Volume 2012 (2012), Article ID 208128, 5 pages doi:10.1155/2012/208128 Qiang Huang and Baozhong Zheng Department of Materials Science and Engineering, Yunnan University, Kunming 650091, China Three benzaldehyde-functionalized ionic liquids were readily synthesized by quaternization of N-alkylimidazole with benzaldehyde-functionalized alkyl bromides under microwave irradiation… Continue reading Facile Synthesis of Benzaldehyde-Functionalized Ionic Liquids and Their Flexible Functional Group Transformations
CES as an Efficient Natural Catalyst for Syn of Schiff Bases under Solvent-Free Conditions: An Innovative Green Approach
CES (calcined eggshell) Organic Chemistry International, Volume 2012 (2012), doi:10.1155/2012/153159 CES as an Efficient Natural Catalyst for Synthesis of Schiff Bases under Solvent-Free Conditions: An Innovative Green Approach Suresh Patil, S. D. Jadhav, and S. K. Shinde Organic Research Laboratory, Department of Chemistry, Padmabhushan Dr. Vasantraodada Patil College, Sangli District, Tasgaon 416312, India http://www.hindawi.com/journals/oci/2012/153159/61695452/ A mild and… Continue reading CES as an Efficient Natural Catalyst for Syn of Schiff Bases under Solvent-Free Conditions: An Innovative Green Approach
One-Pot Synthesis of Alkyl Styryl Sulfides Free from Transition Metal/Ligand Catalyst and Thiols
One-Pot Synthesis of Alkyl Styryl Sulfides Free from Transition Metal/Ligand Catalyst and Thiols http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201201163/abstract European Journal of Organic Chemistry Early View (Online Version of Record published before inclusion in an issue) Adrián A. Heredia and Alicia B. Peñéñory Article first published online: 19 DEC 2012 | DOI: 10.1002/ejoc.201201163 They have developed a one-pot methodology for the… Continue reading One-Pot Synthesis of Alkyl Styryl Sulfides Free from Transition Metal/Ligand Catalyst and Thiols
Total Synthesis and Structure Confirmation of Cryptocaryol A
Total Synthesis and Structure Confirmation of Cryptocaryol A European journal of chemistryEarly View (Online Version of Record published before inclusion in an issue) D. Srinivas Reddy and Debendra K. Mohapatra Article first published online: 19 DEC 2012 | DOI: 10.1002/ejoc.201201309 Maruoka asymmetric allylation, chelation-controlled 1,3-induced allylation, iterative iodocyclization and ring-closing metathesis reactions were used sequentially… Continue reading Total Synthesis and Structure Confirmation of Cryptocaryol A
Pinnick oxidation
The Pinnick oxidation is also known as Lindgren oxidation. It is an organic reaction by which aldehydes can be oxidized into its corresponding carboxylic acid, originally developed by Lindgren and Nilsson.ref1 The typical reaction condition used today was modified by G. A. Kraus even before Pinnick.ref2,3 Pinnick proved this condition as general. There are number of ways to oxidize the aldehydes however, only… Continue reading Pinnick oxidation
US 6894199, Process for the production of xylitol
(2R,4S)-Pentane-1,2,3,4,5-pentol Xylitol used to denote sugar alcohols) is a sugar alcohol sweetener used as a sugar substitute. Xylitol has the formula (CHOH)3(CH2OH)2 and is an achiral isomer of pentane-1,2,3,4,5-pentol. Xylitol is roughly as sweet as sucrose with 33% fewer calories. Unlike other sweeteners, xylitol is actively beneficial for dental health, reducing caries to a third in regular use, and has been shown to reduce… Continue reading US 6894199, Process for the production of xylitol
Sucampo and Abbott Announce Launch of AMITIZA in Japan, 26 nov 2012
Sucampo and Abbott Announce Launch of AMITIZA in Japan Product is Japan’s Only Prescription Medicine for Chronic Constipation Lubiprostone CAS number 136790-76-6 Sucampo Pharmaceuticals, Inc. and Abbott today announced the availability of AMITIZA® (lubiprostone) in Japan, a prescription medicine for the treatment of chronic constipation not caused by organic diseases. AMITIZA was approved by the Ministry of Health,… Continue reading Sucampo and Abbott Announce Launch of AMITIZA in Japan, 26 nov 2012