The five arms of the inhibitor match up to the five B subunits of cholera http://www.rsc.org/chemistryworld/2013/05/cholera-toxin-inhibitor-pentavalent-scaffold-gm1-calixarene Share this:
Tag: ORGANIC CHEMISTRY
Gugulipid, an Extract of Ayurveda Medicine Plant Commiphora Mukul as a Potent Agent for Cancer Chemoprevention and Cancer Chemotherapy
E-Guggulsterone Z-Guggulsterone http://www.omicsonline.org/2161-0444/2161-0444-2-e105.php?%20aid=9899 Citation: Xiao M, Xiao D (2012) Gugulipid, an Extract of Ayurveda Medicine Plant Commiphora Mukul as a Potent Agent for Cancer Chemoprevention and Cancer Chemotherapy. Med chem 2:e105. doi:10.4172/2161-0444.1000e105 Department of Urology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15232, USA Gugulipid (GL), an extract of Commiphora mukul, has been… Continue reading Gugulipid, an Extract of Ayurveda Medicine Plant Commiphora Mukul as a Potent Agent for Cancer Chemoprevention and Cancer Chemotherapy
The Bingel reaction in fullerene chemistry
Bingel fullerene The Bingel reaction in fullerene chemistry The Bingel reaction in fullerene chemistry is a fullerene cyclopropanation reaction to a methanofullerene first discovered by C. Bingel in 1993 with the bromo derivative of diethyl malonate in the presence of a base such as sodium hydride or DBU.[1] The preferred double bonds for this reaction on the fullerene surface are the shorter bonds at the junctions of two hexagons (6-6 bonds) and the driving… Continue reading The Bingel reaction in fullerene chemistry
Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)
Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)Alejandro J. Cagnoni, Oscar Varela, María Laura Uhrig and José Kovensky European Journal of Organic Chemistry Volume 2013, Issue 5, pages 972–983, February 2013 Article first published online: 13 DEC 2012 | DOI: 10.1002/ejoc.201201412 http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201201412/abstract Ruthenium-catalyzed cycloaddition of… Continue reading Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)
Immunosuppressant Drug Rapamycin Helps Preserving Female Fertility
Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidneytransplants. It prevents activation of T cells and B cells by inhibiting their response tointerleukin-2 (IL-2). A macrolide, sirolimus was discovered by Brazilian researchers as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island[1] — an island also known as Rapa Nui.[2] It was approved by the… Continue reading Immunosuppressant Drug Rapamycin Helps Preserving Female Fertility
(Z)-5-tetradecen-1-ol, Potential female sex attractant
Follow my blog with Bloglovin (Z)-5-Tetradecen-1-ol, mw 212.37, formula C14H20O CAS 40642-42-0 Odorant receptors, present on nasal sensory neurons, perceive volatile compounds and regulate animal behavior such as reproduction. The nature of the ligands interacting with these receptors is, however, largely unknown. Keiichi Yoshikawa and colleagues, University of Tokyo, Japan, shed new light on this… Continue reading (Z)-5-tetradecen-1-ol, Potential female sex attractant
Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2’-Deoxy and 2’,3’-Dideoxynucleosides
Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2’-Deoxy and 2’,3’-Dideoxynucleosides http://www.publish.csiro.au/nid/51/paper/CH12426.htm Bo Shen and Timothy F. Jamison Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. Australian Journal of Chemistry – http://dx.doi.org/10.1071/CH12426 Published online: 19 November 2012 http://www.publish.csiro.au/nid/51/paper/CH12426.htm With the development of a new photochemical flow reactor, a multi-step sequence in… Continue reading Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2’-Deoxy and 2’,3’-Dideoxynucleosides
Synthesis of vitamin E
The α-tocopherol form of vitamin E Vitamin E refers to a group of eight fat-soluble compounds that include both tocopherolsand tocotrienols.[1] There are many different forms of vitamin E, of which γ-tocopherol is the most common in the North American diet.[2] γ-Tocopherol can be found in corn oil, soybean oil, margarine and dressings.[3][4] In the North American diet, α-Tocopherol, the most biologically active form… Continue reading Synthesis of vitamin E
IONIC LIQUIDS, USES
Ionic liquids are very popular materials and they enjoy a plethora of applications in various domains of physical sciences. For example, they are used as “solvents” for organic, organometallic syntheses and catalysis, as electrolytes in electrochemistry, in fuel and solar cells, as lubricants, as a stationary phase for chromatography, as matrices for mass spectrometry,… Continue reading IONIC LIQUIDS, USES
Barium Dichloride as a Powerful and Inexpensive Catalyst for the Pechmann Condensation without Using Solvent
Barium Dichloride as a Powerful and Inexpensive Catalyst for the Pechmann Condensation without Using Solvent Saeed Khodabakhshi Department of Chemistry, Islamic Azad University, Gachsaran Branch, Gachsaran, Iran, Organic Chemistry International Volume 2012 (2012), Article ID 306162, 5 pages doi:10.1155/2012/306162 http://www.hindawi.com/journals/oci/2012/306162/ General Procedure for the Preparation of Coumarin 3 A mixture of phenol 1 (1 mmol), β-ketoesters 2 (1 mmol), and… Continue reading Barium Dichloride as a Powerful and Inexpensive Catalyst for the Pechmann Condensation without Using Solvent