DR ANTHONY MELVIN CRASTO Ph.D

AYURVEDA–Manjishta, Rubia cordifolia

Rubia cordifolia Rubia cordifolia Scientific classification Kingdom: Plantae (unranked): Angiosperms (unranked): Eudicots (unranked): Asterids Order: Gentianales Family: Rubiaceae Tribe: Rubieae Genus: Rubia Species: R. cordifolia Binomial name Rubia cordifolia L. Rubia cordifolia, often known as Common Madder or Indian Madder, is a species of flowering plant in the coffee family, Rubiaceae. It has been… Continue reading AYURVEDA–Manjishta, Rubia cordifolia

Gugulipid, an Extract of Ayurveda Medicine Plant Commiphora Mukul as a Potent Agent for Cancer Chemoprevention and Cancer Chemotherapy

E-Guggulsterone Z-Guggulsterone http://www.omicsonline.org/2161-0444/2161-0444-2-e105.php?%20aid=9899 Citation: Xiao M, Xiao D (2012) Gugulipid, an Extract of Ayurveda Medicine Plant Commiphora Mukul as a Potent Agent for Cancer Chemoprevention and Cancer Chemotherapy. Med chem 2:e105. doi:10.4172/2161-0444.1000e105 Department of Urology, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15232, USA Gugulipid (GL), an extract of Commiphora mukul, has been… Continue reading Gugulipid, an Extract of Ayurveda Medicine Plant Commiphora Mukul as a Potent Agent for Cancer Chemoprevention and Cancer Chemotherapy

The Bingel reaction in fullerene chemistry

Bingel fullerene The Bingel reaction in fullerene chemistry The Bingel reaction in fullerene chemistry is a fullerene cyclopropanation reaction to a methanofullerene first discovered by C. Bingel in 1993 with the bromo derivative of diethyl malonate in the presence of a base such as sodium hydride or DBU.[1] The preferred double bonds for this reaction on the fullerene surface are the shorter bonds at the junctions of two hexagons (6-6 bonds) and the driving… Continue reading The Bingel reaction in fullerene chemistry

Organic India launches single ingredient Moringa products in US

Moringa oleifera The Drumstick Plant http://miracletrees.org/ 08 February 2013, Organic India, a manufacturer of herb-based functional supplements, has launched organic single ingredient Moringa products in the US. Available in both capsule and powder formulations, the product made from powdered leaves of Moringa oleifera tree contains vitamin A, B1, B3, B12, iron, magnesium, potassium, amino acids, and… Continue reading Organic India launches single ingredient Moringa products in US

Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)

Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)Alejandro J. Cagnoni, Oscar Varela, María Laura Uhrig and José Kovensky European Journal of Organic Chemistry Volume 2013, Issue 5, pages 972–983, February 2013 Article first published online: 13 DEC 2012 | DOI: 10.1002/ejoc.201201412 http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201201412/abstract Ruthenium-catalyzed cycloaddition of… Continue reading Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition Reaction of Disubstituted Alkynes on Carbohydrate Scaffolds (pages 972–983)

Immunosuppressant Drug Rapamycin Helps Preserving Female Fertility

Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidneytransplants. It prevents activation of T cells and B cells by inhibiting their response tointerleukin-2 (IL-2). A macrolide, sirolimus was discovered by Brazilian researchers as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island[1] — an island also known as Rapa Nui.[2] It was approved by the… Continue reading Immunosuppressant Drug Rapamycin Helps Preserving Female Fertility

FDA Approves Ravicti (glycerol phenylbutyrate)for the Chronic Management of Some Urea Cycle Disorders

FDA Approves Ravicti (glycerol phenylbutyrate)for the Chronic Management of Some Urea Cycle Disorders Ravicti is marketed by Hyperion Therapeutics, based in South San Francisco, Calif. February 1, 2013 — The U.S. Food and Drug Administration today approved Ravicti (glycerol phenylbutyrate) for the chronic management of some urea cycle disorders (UCDs) in patients ages 2 years… Continue reading FDA Approves Ravicti (glycerol phenylbutyrate)for the Chronic Management of Some Urea Cycle Disorders

Chinese Plant Compound , Triptolide Wipes out Cancer in 40 Days, Say new Research.

Triptolide is a diterpenoid epoxide found in the Thunder God Vine, Tripterygium wilfordii. It has in vitro and in vivo activities against mouse models of polycystic kidney disease[1] and pancreatic cancer, but its physical properties limit its therapeutic potential.[2] Consequently, a synthetic prodrug, minnelide, is being studied clinically instead.[2] A little-known plant with a truly… Continue reading Chinese Plant Compound , Triptolide Wipes out Cancer in 40 Days, Say new Research.

(Z)-5-tetradecen-1-ol, Potential female sex attractant

Follow my blog with Bloglovin (Z)-5-Tetradecen-1-ol, mw 212.37, formula C14H20O CAS 40642-42-0 Odorant receptors, present on nasal sensory neurons, perceive volatile compounds and regulate animal behavior such as reproduction. The nature of the ligands interacting with these receptors is, however, largely unknown. Keiichi Yoshikawa and colleagues, University of Tokyo, Japan, shed new light on this… Continue reading (Z)-5-tetradecen-1-ol, Potential female sex attractant

AT13148, Drug Blocks Multiple Cancer Causes

AT13148 AT13148 is a multi-AGC kinase, ATP-competitive inhibitor, identified utilizing high-throughput X-ray crystallography and fragment-based lead discovery techniques. AT13148 caused substantial blockade of AKT, p70S6K, PKA, ROCK and SGK substrate phosphorylation and induction of apoptosis in both a concentration and time-dependent manner in cancer cells with clinically relevant genetic defects both in vitro and in… Continue reading AT13148, Drug Blocks Multiple Cancer Causes