Tag: WORLD DRUG TRACKER

Crystal structure closes classic carbocation case

  Herb Brown favoured rapidly equilibrating classical enantiomers of the 2-norbornyl cation Winstein proposed the nonclassical structure of the 2-norbornyl cation, now shown to be correct F Scholz et al, Science, 2013, DOI: 10.1126/science.1238849 After more than 60 years, crystals of the 2-norbornyl cation have finally put its ‘nonclassical’ structure, with a pentacoordinate carbon, beyond… Continue reading Crystal structure closes classic carbocation case

Visible-light mediated heterogeneous C-H functionalization: oxidative multi-component reactions using a recyclable titanium dioxide (TiO2) catalyst

  Green Chem., 2013, Advance Article DOI: 10.1039/C3GC40587G, Communication Carlos Vila, Magnus Rueping RWTH Aachen University, Institute of Organic Chemistry, Landoltweg 1, D-52074 Aachen, Germany A new multi-component protocol employing visible-light catalysis using a cheap, robust, readily available and recyclable titanium dioxide catalyst provides a series of [small alpha]-amino amides. Visible-light mediated heterogeneous C-H functionalization:… Continue reading Visible-light mediated heterogeneous C-H functionalization: oxidative multi-component reactions using a recyclable titanium dioxide (TiO2) catalyst

Star-Shaped Macromolecule Grabs Large Anions-Chemists at Indiana University Bloomington have created a symmetrical, five-sided macrocycle that is easy to synthesize and has characteristics that may help expand the molecular tool box available to researchers in biology, chemistry and materials sciences.

cure for diabetes This model shows the five-sided cyanostar macrocycle capturing perchlorate at its center. (Credit: Amar Flood)], Chemists at Indiana University Bloomington have created a symmetrical, five-sided macrocycle that is easy to synthesize and has characteristics that may help expand the molecular tool box available to researchers in biology, chemistry and materials sciences.The molecule,… Continue reading Star-Shaped Macromolecule Grabs Large Anions-Chemists at Indiana University Bloomington have created a symmetrical, five-sided macrocycle that is easy to synthesize and has characteristics that may help expand the molecular tool box available to researchers in biology, chemistry and materials sciences.

China Homecoming– As funding grows, more Chinese chemists who have studied abroad are returning home to become professors

INVESTING Graduate student Zepeng Yang at work in You’s laboratory at the Shanghai Institute of Organic Chemistry. Credit: Shuli You/ Shanghai Institute of Organic Chemistry http://cen.acs.org/articles/91/i23/China-Homecoming.html

Coenzyme Q10

Coenzyme Q10 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5, 6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione Coenzyme Q10 (ubiquinone-10, CoQ10, CoQ, Q10 or simply Q) is aubiquinone containing 10 isoprenoid units. First discovered in 1957 by Crane et al. [1], its chemical structure was determined by Karl Folkers [2], who later won the Priestley medal from the American Chemical Society. This oil-soluble, vitamin-like micronutrient forms part of the electron transport chain which, in the process of… Continue reading Coenzyme Q10

“Crystal-clear” method distinguishes between glass and fluids

The colloids that were used for the model: particles, each with a diameter of approximately 150 nm, suspended in water. The solid nucleus consists of the plastic polystyrene, the surrounding shell of a thermosensitive poly(N-isopropyl-acrylamide) network. By lowering the temperature, each individual particle’s volume—and, by definition, its packing density—can be increased. Photo: HZB/M. Siebenbürger Many… Continue reading “Crystal-clear” method distinguishes between glass and fluids

Fluoride’s Unexpected Role In Photocatalysis-Materials: Acid’s surface residue, not just the catalyst, should get credit

Using HF in TiO2 synthesis (left) changes the crystals’ morphologies and facets relative to an HF-free method (right), as seen in these TEM images, and may unexpectedly alter the crystals’ catalytic properties. Credit: ACS Catal read all at http://cen.acs.org/articles/91/i21/Fluorides-Unexpected-Role-Photocatalysis.html