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vitamin b12 – EUREKAMOMENTS IN ORGANIC CHEMISTRY https://amcrasto.theeurekamoments.com DR ANTHONY MELVIN CRASTO Ph.D, WorldDrugTracker, Glenmark scientist ( Ph.D, ICT) helping millions with chemistry websites, million hits on google sites, Intention is to help chemists across the world, content is academic Fri, 02 Aug 2013 07:36:38 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 Vitamin B12: chemical modifications https://amcrasto.theeurekamoments.com/2013/07/31/vitamin-b12-chemical-modifications/ Wed, 31 Jul 2013 07:45:11 +0000 http://amcrasto.theeurekamoments.com/?p=1033 Continue reading Vitamin B12: chemical modifications]]>

Chem. Soc. Rev., 2013, 42,6605-6619
DOI: 10.1039/C3CS60062A, Tutorial Review
Keith o Proinsias, Maciej Giedyk, Dorota Gryko
Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland 
E-mail: dorota.gryko@icho.edu.pl
Lord Alexander B. Todd wrote: “Vitamin B12turned out to be a substance of frightening complexity“. This review focuses on the chemistry of this complex molecule and its derivatives giving the researcher an introduction to the field of this fascinating molecule.

Vitamin B12: chemical modifications

Vitamin B12 plays a key role in many metabolic processes occurring in all mammals. Over the years its biological role has been extensively studied generating a lot of interest in the chemistry of this vital molecule. This established a variety of new methodologies for the synthesis and analysis of new cobalamin derivatives as well as creative purification techniques. This tutorial review summarizes all the advancements made in this area, providing a deeper insight into vitamin B12 chemistry.

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