DOI: 10.1039/C3CS60062A, Tutorial Review
E-mail: dorota.gryko@icho.edu.pl
Lord Alexander B. Todd wrote: “Vitamin B12turned out to be a substance of frightening complexity“. This review focuses on the chemistry of this complex molecule and its derivatives giving the researcher an introduction to the field of this fascinating molecule.
Vitamin B12: chemical modifications
Vitamin B12 plays a key role in many metabolic processes occurring in all mammals. Over the years its biological role has been extensively studied generating a lot of interest in the chemistry of this vital molecule. This established a variety of new methodologies for the synthesis and analysis of new cobalamin derivatives as well as creative purification techniques. This tutorial review summarizes all the advancements made in this area, providing a deeper insight into vitamin B12 chemistry.
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amcrasto@gmail.com
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The cuboctahedron consists of copper paddle-wheel nodes and carborane–isophthalic acids
Scientists in the US have made a molecular species containing the highest number of boron atoms ever recorded in a crystallographically characterised molecular species. The unique supramolecular cuboctahedron contains 240 boron atoms and was synthesised by Chad Mirkin and colleagues at Northwestern University in Evanston, Illinois, via coordination-driven assembly.
http://www.rsc.org/chemistryworld/2013/07/nanostructure-highest-number-boron-atoms
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The molecule of about 2 nm in size is kept stable between two metal electrodes for several days. Image: Christian Grupe/KIT
A team of physicists has succeeded in performing an extraordinary experiment: They demonstrated how magnetism that generally manifests itself by a force between two magnetized objects acts within a single molecule. This discovery is of high significance to fundamental research and provides scientists with a new tool to better understand magnetism as an elementary phenomenon of physics. The researchers published their results in the latest issue of Nature Nanotechnology.
The smallest unit of a magnet is the magnetic moment of a single atom or ion. Researchers in Germany wanted to find out whether the magnetism of a pair of magnetic moments can be measured electrically in a single molecule. To do this, they succeeded in performing an extraordinary experiment which shows how magnetism that generally manifests itself by a force between two magnetized objects acts within a single molecule.
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This model shows the role of vesicles, vesicle chains and membrane tubes in M. xanthus biofilms. The scientists believe these connections help cells exchange signals and material. Image: Auer laboratory
Using several imaging techniques, Lawrence Berkeley National Laboratory scientists found that a common soil bacterium stays connected by a network of chain-like membranes. They believe the bacterium uses its network to coordinate social activities-such as evading bacterial enemies and snaring prey-without revealing its location. Even bacteria use social networks
read at
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The structure of a single water molecule imprisoned inside a fullerene C60 at equilibrium (left), and projection trajectories of the encapsulated H2O molecule (mass center) within one period for steady-state transport of H2O@C60 under an electric intensity of 0.05 V/Å(right).
read all at
http://www.engineering.columbia.edu/nanotechnology-breakthrough-may-improve-drug-delivery
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