The N-methylation of electron-deficient pyrroles was affected using dimethyl carbonate in the presence of DMF and catalytic DABCO. This alkylation methodology has proven useful for the alkylation of a variety of pyrroles in 72−98% yields and is considered to be greenchemistry relative to the more common use of methyl halides or dimethyl sulfate. Michael L. Laurila , Nicholas A.… Continue reading Green N-Methylation of Electron Deficient Pyrroles with Dimethylcarbonate