The Formal Total Synthesis of FR252921 – An Immunosuppressant European Journal of Organic Chemistry Volume 2013, Issue 2, pages 376–388, January 2013 J. S. Yadav and Sandip Sengupta Article first published online: 15 NOV 2012 | DOI: 10.1002/ejoc.201201097 http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201201097/abstract The formal total synthesis of FR252921 is described. The key steps include the preparation of… Continue reading The Formal Total Synthesis of FR252921 – An Immunosuppressant
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Total Synthesis and Structure Confirmation of Cryptocaryol A
Total Synthesis and Structure Confirmation of Cryptocaryol A European journal of chemistryEarly View (Online Version of Record published before inclusion in an issue) D. Srinivas Reddy and Debendra K. Mohapatra Article first published online: 19 DEC 2012 | DOI: 10.1002/ejoc.201201309 Maruoka asymmetric allylation, chelation-controlled 1,3-induced allylation, iterative iodocyclization and ring-closing metathesis reactions were used sequentially… Continue reading Total Synthesis and Structure Confirmation of Cryptocaryol A
AVANAFIL, NEW DRUG FOR ERECTILE DYSFUNCTION, FDA APRIL 2012
Avanafil is a PDE5 inhibitor approved for erectile dysfunction on April 27, 2012.[1] Avanafil is known by the trademark name Stendra and was developed by Vivus Inc. It acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are sildenafil, tadalafil and vardenafil. The advantage of avanafil is that… Continue reading AVANAFIL, NEW DRUG FOR ERECTILE DYSFUNCTION, FDA APRIL 2012
cis z jasmone
Jasmone is a natural organic compound extracted from the volatile portion of the oil fromjasmine flowers. It is a colorless to pale yellow liquid that has the odor of jasmine. Jasmone can exist in two isomeric forms with differing geometry around the pentenyl double bond, cis-jasmone and trans-jasmone. The natural extract contains only the cis form, while synthetic material is often… Continue reading cis z jasmone
A GREEN CHEMICAL APPROACH FOR NITRATION OF AROMATIC COMPOUNDS
https://docs.google.com/viewer?url=http%3A%2F%2Fwww.mjcce.org.mk%2FPDF%2F28_2_425.pdf A GREEN CHEMICAL APPROACH FOR NITRATION OF AROMATIC COMPOUNDS Arpita Dugar, Anil Kumar, Rameshwar Ameta, Suresh C. AmetaMACEDONIAN JOURNAL OF CHEM AND CHEM ENG, 2009, V28,2, PG 163 Photochemical aromatic nitration of phenol and salicylic acid has been carried out in the presence of UV radiations and formation of products has been observed spectrophotometrically.… Continue reading A GREEN CHEMICAL APPROACH FOR NITRATION OF AROMATIC COMPOUNDS
SUGAR MANUFACTURING
The initial stage involves sampling, weighing and washing the sugarcane. From there the material passes to can crushers and then into the mill. The bagasse, which results from the milling, is used in the boilers for steam production that is used to power the process. The surplus bagasse from this stage is used in industry.… Continue reading SUGAR MANUFACTURING
COLOURFUL MECHANISMS-ACADEMIC HELP
Epoxidation OZONOLYSIS oxidations DIELS ALDER RXN We noted earlier that addition reactions of alkenes often exhibited STEREOSPEFICITY, in that the reagent elements in some cases added syn and in other cases anti to the the plane of the double bond. Both reactants in the Diels-Alder reaction may demonstrate stereoisomerism, and when they do it is… Continue reading COLOURFUL MECHANISMS-ACADEMIC HELP
Cram’s rule
The Cram’s rule of asymmetric induction developed by Donald J. Cram in 1952, is an early concept relating to the prediction of stereochemistry in certain acyclic systems. In full the rule is: In certain non-catalytic reactions that diastereomer will predominate, which could be formed by the approach of the entering group from the least hindered side… Continue reading Cram’s rule
HOECHST MARION ROUSSEL
I WAS A PART PROCESS DEVELOPMENT LAB , MULUND, MUMBAI, INDIA, HEAD, DR RALPH STAPEL IN CENTRE
IMATINIB…..
Medicine for Blood Cancer ‘Imitinef Mercilet’ is a medicine which cures blood cancer. Its available free of cost at “Adyar Cancer Institute in Chennai”. Create Awareness. It might help someone.Cancer Institute in Adyar, Chennai ‘Imitinef Mercilet’ is apparently an alternative spelling of the drug Imatinib mesylate which is used in the treatment of some… Continue reading IMATINIB…..