Deprecated: Return type of Endurance_Collection::offsetExists($key) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home4/theeurek/public_html/amcrasto/wp-content/plugins/bluehost-wordpress-plugin/vendor/bluehost/endurance-wp-module-loader/includes/Collection.php on line 418

Deprecated: Return type of Endurance_Collection::offsetGet($key) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home4/theeurek/public_html/amcrasto/wp-content/plugins/bluehost-wordpress-plugin/vendor/bluehost/endurance-wp-module-loader/includes/Collection.php on line 429

Deprecated: Return type of Endurance_Collection::offsetSet($key, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home4/theeurek/public_html/amcrasto/wp-content/plugins/bluehost-wordpress-plugin/vendor/bluehost/endurance-wp-module-loader/includes/Collection.php on line 439

Deprecated: Return type of Endurance_Collection::offsetUnset($key) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home4/theeurek/public_html/amcrasto/wp-content/plugins/bluehost-wordpress-plugin/vendor/bluehost/endurance-wp-module-loader/includes/Collection.php on line 452

Deprecated: Return type of Endurance_Collection::count() should either be compatible with Countable::count(): int, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home4/theeurek/public_html/amcrasto/wp-content/plugins/bluehost-wordpress-plugin/vendor/bluehost/endurance-wp-module-loader/includes/Collection.php on line 82

Deprecated: Return type of Endurance_Collection::getIterator() should either be compatible with IteratorAggregate::getIterator(): Traversable, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /home4/theeurek/public_html/amcrasto/wp-content/plugins/bluehost-wordpress-plugin/vendor/bluehost/endurance-wp-module-loader/includes/Collection.php on line 219
Synthesis of Chiral Pyridylphenols for the Enantioselective Addition of Diethylzinc to Aldehydes – EUREKAMOMENTS IN ORGANIC CHEMISTRY

Synthesis of Chiral Pyridylphenols for the Enantioselective Addition of Diethylzinc to Aldehydes

很高兴看到来自中国的精彩文章

http://onlinelibrary.wiley.com/doi/10.1002/jccs.201100474/abstract

DOI: 10.1002/jccs.201100474

Chiral 8-substituted 2-(8,10,10-trimethyl-6-aza-tricyclo[7.1.1.02,7]undeca-2(7),3,5-trien-5-yl)-phenols were prepared from a high enantiopurity (>97% ee) of (1R)-(+)-alpha-pinene, and assessed in the enantioselective addition of diethylzinc to substituted benzaldehydes, giving the (S)-alcohols with enantiomeric excess ranging from 33% to 89%. Interestingly, in all cases, except for those of ortho-chlorobenzaldehyde, ortho- and para-methoxybenzaldehydes, the ee was >71%.