Seeding removes barrier to curious cocrystal

Once the heteronuclear seeds had been used in the lab, the cocrystal formed regardless of whether or not the seeds were used

The caffeine•benzoic acid cocrystal that has eluded scientists for 60 years has finally been crystallised

Cocrystals are crystalline materials composed of two or more molecules held together within the same crystal lattice. Cocrystallisation is significant in the pharmaceutical industry, where drug molecules are screened for cocrystal formation in order to improve their solubility, stability and bioavailability. This has the added advantage of increasing the number of crystal forms that can be considered for drug formulation while simultaneously maximising patent protection.

Seeding removes barrier to curious cocrystal

READ ALL AT

http://www.rsc.org/chemistryworld/2013/08/caffeine-benzoic-acid-cocrystal

http://blogs.rsc.org/nj/2012/07/23/how-good-are-the-crystallisation-methods-for-co-crystals/

Share this:
Share this page via Email Share this page via Stumble Upon Share this page via Digg this Share this page via Facebook Share this page via Twitter

About DR ANTHONY MELVIN CRASTO Ph.D

DR ANTHONY MELVIN CRASTO Ph.D,( ICT), Worlddrugtracker, Helping millions with chemistry sites, million hits on google
This entry was posted in SYNTHESIS and tagged , , , , , , , . Bookmark the permalink.