Barium Dichloride as a Powerful and Inexpensive Catalyst for the Pechmann Condensation without Using Solvent
Department of Chemistry, Islamic Azad University, Gachsaran Branch, Gachsaran, Iran, Organic Chemistry International
Volume 2012 (2012), Article ID 306162, 5 pages
General Procedure for the Preparation of Coumarin 3
A mixture of phenol 1 (1 mmol), β-ketoesters 2 (1 mmol), and barium dichloride (10 mol%) was heated and stirred at 100°C. After completion of the reaction (controlled by TLC), the reaction mixture was cooled at room temperature and poured onto crushed ice. The solid product obtained was filtered off, washed with ice-cold water, and recrystallized from hot EtOH to obtain the pure product 3.