http:\/\/www.publish.csiro.au\/nid\/51\/paper\/CH12426.htm<\/a><\/p>\nWith the development of a new photochemical flow reactor, a multi-step sequence in continuous flow afforded deoxynucleoside drugs in high efficiency.<\/p>\n
A new photochemical flow reactor has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2\u2032-deoxy and 2\u2032,3\u2032-dideoxynucleosides. The continuous flow format significantly improved both the efficiency and selectivity of the reaction, with the streamlined multi-step sequence directly furnishing the highly desired unprotected deoxynucleosides.<\/p>\n","protected":false},"excerpt":{"rendered":"
Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2\u2019-Deoxy and 2\u2019,3\u2019-Dideoxynucleosides\u00a0http:\/\/www.publish.csiro.au\/nid\/51\/paper\/CH12426.htm Bo Shen and Timothy F. Jamison Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. Australian Journal of Chemistry – http:\/\/dx.doi.org\/10.1071\/CH12426 Published online: 19 November 2012 http:\/\/www.publish.csiro.au\/nid\/51\/paper\/CH12426.htm With the development of a new photochemical flow reactor, a multi-step sequence in… Continue reading Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2\u2019-Deoxy and 2\u2019,3\u2019-Dideoxynucleosides<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,1],"tags":[143],"_links":{"self":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/514"}],"collection":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/comments?post=514"}],"version-history":[{"count":4,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/514\/revisions"}],"predecessor-version":[{"id":520,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/514\/revisions\/520"}],"wp:attachment":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/media?parent=514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/categories?post=514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/tags?post=514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}