Synthesis<\/h2>\n

Avanafil can be synthesized from a benzylamine derivative and a pyrimidine derivative:^{[2]<\/a><\/sup><\/p>\n}

\n

\n

\n
1. <\/strong>“FDA approves Stendra for erectile dysfunction”<\/a>\u00a0(Press release).\u00a0Food and Drug Administration<\/a>\u00a0(FDA). April 27, 2012.<\/li>\n
2. <\/strong>Yamada, K.; Matsuki, K.; Omori, K.; Kikkawa, K.; 2004,\u00a0U.S. Patent 6,797,709<\/a><\/li>\n<\/ol>\n

   <\/a><\/p>\n<\/dd>\n<\/dl>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

   \n

   links<\/h2>\n

   \n

   \n
   • Faster-Working Erectile Dysfunction Drug?<\/a>. CBS News. November 24, 2009.<\/li>\n
   • Vivus says men taking avanafil were more likely to be ready for sex within 15 minutes<\/a>.\u00a0The Gaea Times<\/em>. January 11, 2010.<\/li>\n
   • “Avanafil is the New Player in The Erectile Dysfunction Field”<\/a>. June 28, 2011<\/li>\n
   • <\/li>\n
   • NAME—4-[(3-Chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide<\/wbr><\/li>\n<\/ul>\n<\/div>\n

     <\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

     Avanafil\u00a0is a\u00a0PDE5 inhibitor\u00a0approved for\u00a0erectile dysfunction\u00a0on April 27, 2012.[1]\u00a0Avanafil is known by the trademark name Stendra and was developed by\u00a0Vivus Inc.\u00a0It acts by inhibiting a specific\u00a0phosphodiesterase\u00a0type 5 enzyme which is found in various body tissues, but primarily in the\u00a0corpus cavernosum penis, as well as the retina. Other similar drugs are\u00a0sildenafil,\u00a0tadalafil\u00a0and\u00a0vardenafil. The advantage of avanafil is that… Continue reading AVANAFIL, NEW DRUG FOR ERECTILE DYSFUNCTION, FDA APRIL 2012<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13,1],"tags":[12],"_links":{"self":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/346"}],"collection":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/comments?post=346"}],"version-history":[{"count":9,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/346\/revisions"}],"predecessor-version":[{"id":351,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/346\/revisions\/351"}],"wp:attachment":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/media?parent=346"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/categories?post=346"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/tags?post=346"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}