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{"id":249,"date":"2012-11-15T07:26:45","date_gmt":"2012-11-15T07:26:45","guid":{"rendered":"http:\/\/amcrasto.theeurekamoments.com\/?p=249"},"modified":"2012-11-16T10:57:06","modified_gmt":"2012-11-16T10:57:06","slug":"a-mild-room-temperature-protection-of-ketones-and-aldehydes-as-13-%c2%addioxolanes-under-basic-conditions","status":"publish","type":"post","link":"https:\/\/amcrasto.theeurekamoments.com\/2012\/11\/15\/a-mild-room-temperature-protection-of-ketones-and-aldehydes-as-13-%c2%addioxolanes-under-basic-conditions\/","title":{"rendered":"A Mild, Room-Temperature Protection of Ketones and Aldehydes as 1,3-\u00adDioxolanes under Basic Conditions"},"content":{"rendered":"

A Mild, Room-Temperature Protection of Ketones and Aldehydes as 1,3-\u00adDioxolanes under Basic Conditions<\/a><\/p>\n

Hassner, Alfred; et al<\/p>\n

Department of Chemistry,Bar-IlanUniversity,Ramat-Gan52900,Israel<\/p>\n

Protection of ketones or aldehydes as 1,3-dioxolane derivatives proceeds within minutes at room temperature in the presence of\u00a0N<\/em>-hydroxybenzenesulfonamide, its\u00a0O<\/em>-benzyl derivative, or the tosyl analogue, in the absence of strong protonic acids, and in the presence of base (Et3<\/sub>N). Acid-sensitive groups such as\u00a0O<\/em>-THP,\u00a0O<\/em>-TBS, or\u00a0N<\/em>-Boc are unaffected.<\/p>\n

\"\/preview\/synlett\/EFirst\/b0225_ga.gif\"<\/p>\n

https:\/\/www.thieme-connect.com\/ejournals\/abstract\/10.1055\/s-0032-1317529\u00a0<\/a><\/p>\n

\"\"<\/p>\n

 <\/p>\n

 <\/p>\n

\"ANTHONY<\/p>\n

THANKS AND REGARD’S
\nDR ANTHONY MELVIN CRASTO Ph.D<\/p>\n

amcrasto@gmail.com<\/a><\/div>\n
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A Mild, Room-Temperature Protection of Ketones and Aldehydes as 1,3-\u00adDioxolanes under Basic Conditions Hassner, Alfred; et al Department of Chemistry,Bar-IlanUniversity,Ramat-Gan52900,Israel Protection of ketones or aldehydes as 1,3-dioxolane derivatives proceeds within minutes at room temperature in the presence of\u00a0N-hydroxybenzenesulfonamide, its\u00a0O-benzyl derivative, or the tosyl analogue, in the absence of strong protonic acids, and in the presence… Continue reading A Mild, Room-Temperature Protection of Ketones and Aldehydes as 1,3-\u00adDioxolanes under Basic Conditions<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[144],"_links":{"self":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/249"}],"collection":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/comments?post=249"}],"version-history":[{"count":4,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/249\/revisions"}],"predecessor-version":[{"id":253,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/posts\/249\/revisions\/253"}],"wp:attachment":[{"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/media?parent=249"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/categories?post=249"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/amcrasto.theeurekamoments.com\/wp-json\/wp\/v2\/tags?post=249"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}