DENDRIMER: A NOVEL SYSTEM IN PHARMACEUTICALS Dendrimers are a new class of synthetic polymers which have a tree or star shape like structure, with a central core, interior branches and terminal groups which embellish the surface. It can be synthesized by a repetitive step-growth polymerization process. They are highly branched and monodisperse… read more: http://www.pharmatutor.org/articles/dendrimer-novel-system-in-pharmaceuticals Crystal… Continue reading DENDRIMER: A NOVEL SYSTEM IN PHARMACEUTICALS
Tag: green chemistry
Physicists Discover Theoretical Possibility of Large, Hollow Magnetic Cage Molecules
Illustration depicts a Mn24C18 cluster carrying a magnetic moment of 70 Bohr magnetons. (Credit: Image courtesy of Menghao Wu, Ph.D./VCU.) Virginia Commonwealth University researchers have discovered, in theory, the possibility of creating large, hollow magnetic cage molecules that could one day be used in medicine as a drug delivery system to non-invasively treat tumors, and… Continue reading Physicists Discover Theoretical Possibility of Large, Hollow Magnetic Cage Molecules
Vitamin B12: chemical modifications
Chem. Soc. Rev., 2013, 42,6605-6619 DOI: 10.1039/C3CS60062A, Tutorial Review Keith o Proinsias, Maciej Giedyk, Dorota Gryko Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland E-mail: dorota.gryko@icho.edu.pl Lord Alexander B. Todd wrote: “Vitamin B12turned out to be a substance of frightening complexity“. This review focuses on the chemistry of this complex molecule and its… Continue reading Vitamin B12: chemical modifications
Highlights from ASMC’13 – Advances in Synthetic and Medicinal Chemistry – May 5-8 2013, Moscow, Russia
Med. Chem. Commun., 2013, 4,1138-1144 DOI: 10.1039/C3MD90017G, Conference Report Edmond Differding EFMC & Differding Consulting, Route de Blocry 55, 1348 Louvain-la-Neuve, Belgium E-mail: edmond@differding.com Received 14 Jun 2013, Accepted 14 Jun 2013 First published online 18 Jul 2013 ASMC’13 Moscow focused on new synthetic methodologies and aimed at expanding the drug discovery space from small to… Continue reading Highlights from ASMC’13 – Advances in Synthetic and Medicinal Chemistry – May 5-8 2013, Moscow, Russia
Magnetism of single molecule controlled by voltage
The molecule of about 2 nm in size is kept stable between two metal electrodes for several days. Image: Christian Grupe/KIT A team of physicists has succeeded in performing an extraordinary experiment: They demonstrated how magnetism that generally manifests itself by a force between two magnetized objects acts within a single molecule. This discovery is… Continue reading Magnetism of single molecule controlled by voltage
Synthesis of cyclic carbonates with carbon dioxide and cesium carbonate
Cyclic carbonates are important compounds for the synthesis of biocompatible polymers and linear dialkyl carbonates, as well as solvents and electrolytes. We report here the synthesis of such compounds from easily accessible starting materials with carbon dioxide as a C1 source and caesium carbonate as the base. This new methodology is able to yield… Continue reading Synthesis of cyclic carbonates with carbon dioxide and cesium carbonate
Even bacteria use social networks
This model shows the role of vesicles, vesicle chains and membrane tubes in M. xanthus biofilms. The scientists believe these connections help cells exchange signals and material. Image: Auer laboratory Using several imaging techniques, Lawrence Berkeley National Laboratory scientists found that a common soil bacterium stays connected by a network of chain-like membranes. They… Continue reading Even bacteria use social networks
History of Cyclotides
Cyclotides are head-to-tail cyclic peptides in plants Cyclotides are plant-derived peptides of approximately 30 amino acids. They have the characteristic structural features of a head-to-tail cyclized backbone and a cystine knot arrangement of their three conserved disulfide bonds. Their unique structural features lead to exceptional stability. This and their amenability to chemical synthesis have made… Continue reading History of Cyclotides
Chemists welcome newest member of nanocarbon family
The grossly warped nanographene has interesting optical and electronic properties © NPG A new family of nanocarbons has emerged with the growth of the first non-planar nanographene. Chemists from Boston College, US, and Nagoya University, Japan successfully synthesised a grossly warped nanographene by embedding non-hexagonal rings into a nanographene subunit. The unique structure was found… Continue reading Chemists welcome newest member of nanocarbon family
Marine Natural Products – Bioactivity & Chemical Ecology
Marine Natural Products – Bioactivity & Chemical Ecology allow slideshare to load……… Marine Natural Products – Bioactivity & Chemical Ecology [Kenneth Boyd, Martina Maria Burtscher & Robbie Mutton] from University of the Highlands and Islands