INVESTING Graduate student Zepeng Yang at work in You’s laboratory at the Shanghai Institute of Organic Chemistry. Credit: Shuli You/ Shanghai Institute of Organic Chemistry http://cen.acs.org/articles/91/i23/China-Homecoming.html
Tag: chirality
Cram’s rule
The Cram’s rule of asymmetric induction developed by Donald J. Cram in 1952, is an early concept relating to the prediction of stereochemistry in certain acyclic systems. In full the rule is: In certain non-catalytic reactions that diastereomer will predominate, which could be formed by the approach of the entering group from the least hindered side… Continue reading Cram’s rule