Synthesis of Azadirachtin

Azadirachtin 11141-17-6  cas no Azadirachtin, a chemical compound belonging to the limonoid group, is asecondary metabolite present in neem seeds. It is a highly oxidizedtetranortriterpenoid which boasts a plethora of oxygen functionality, comprising an enol ether, acetal, hemiacetal, and tetra-substituted oxirane as well as a variety of carboxylic esters. This compound is a tetraterpenoid characteristic of the Meliaceae family but particularly from the Neem tree (A. indica), indigenous to… Continue reading Synthesis of Azadirachtin

Sweet Poison, Star fruit neurotoxin identified, caramboxin

    Star fruit neurotoxin identified Neurotoxin from Star Fruit Patients with kidney disease have to watch what they eat: bananas, oranges, tomatoes, nuts, broccoli, and beans are all off-limits. Putting star fruit or carambola on the menu would be downright dangerous. This fruit contains a substance that is a deadly neurotoxin for people with… Continue reading Sweet Poison, Star fruit neurotoxin identified, caramboxin

Pregabalin

  PREGABALIN LEARN ABOUT SPECTRAL DATA AT http://orgspectroscopyint.blogspot.in/2013/11/pregabalin-spectral-data.html Pregabalin (INN) /prɨˈɡæbəlɨn/ is an anticonvulsant drug used for neuropathic pain and as an adjunct therapy for partial seizures with or without secondary generalization in adults.[1] It has also been found effective for generalized anxiety disorder and is (as of 2007) approved for this use in the European Union and Russia. It was designed as a more potent successor to gabapentin. Pregabalin is… Continue reading Pregabalin

Whisky lactone

Whisky Lactone Whisky lactone, also known as β-methyl-γ-octalactone or quercus lactone (from the Latin for oak treeQuercus alba), is a flavouring found in American bourbon whiskies, and is also found in all types of oak. The flavour gets into the whisky when it’s matured in oak barrels. The pure molecule has a fierce, strong, and sweet smell… Continue reading Whisky lactone

Amide Hydrogenation in Flow Reactor

http://www.chemistryviews.org/details/ezine/5392681/Amide_Hydrogenation_in_Flow_Reactor.html Amide Hydrogenation in Flow Reactor (wiley) Amines are produced by amide hydrogenation over a bimetallic platinum–rhenium catalyst in a high-throughput vertical flow reactor Read more http://www.chemistryviews.org/details/ezine/5392681/Amide_Hydrogenation_in_Flow_Reactor.html

Transition-metal-catalyzed C–C bond formation through the fixation ofcarbon dioxide

Carbon dioxide is an important carbon source in the atmosphere and is “problematic” toward the activities of human beings. Although carbon dioxide is a cheap, abundant and relatively nontoxic C1 source, its chemical transformations have not been widely developed so far and are still far from synthetic applications, especially in the construction of the C–C… Continue reading Transition-metal-catalyzed C–C bond formation through the fixation ofcarbon dioxide

Green N-Methylation of Electron Deficient Pyrroles with Dimethylcarbonate

The N-methylation of electron-deficient pyrroles was affected using dimethyl carbonate in the presence of DMF and catalytic DABCO. This alkylation methodology has proven useful for the alkylation of a variety of pyrroles in 72−98% yields and is considered to be greenchemistry relative to the more common use of methyl halides or dimethyl sulfate. Michael L. Laurila , Nicholas A.… Continue reading Green N-Methylation of Electron Deficient Pyrroles with Dimethylcarbonate

Article On Alternative Solvents:  Shades of Green

The use of alternative reaction solvents is reviewed in terms of life cycle. Supercritical CO2, ionic liquids, fluorous solvents, water, and renewable organics are compared on the basis of their solvency, ease of use, reusability, health and safety, environmental impact, and economic cost. James H. Clark * and Stewart J. Tavener Green Chemistry Centre, Department of Chemistry, University… Continue reading Article On Alternative Solvents:  Shades of Green