Category Archives: Uncategorized

DEFLAZACORT

Deflazacort CAS 14484-47-0 Molecular Formula C25H31NO6 Average mass 441.517 Da (11b,16b)-21-(Acetyloxy)-11-hydroxy-2′-methyl-5’H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 11b,21-Dihydroxy-2′-methyl-5’bH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 21-acetate 2-[(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-Hydroxy-4a,6a,8-trimethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2′,1′:4,5]indeno[1,2-d][1,3]oxazol-6b-yl]-2-oxoethyl acetate 5’βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11β,21-dihydroxy-2′-methyl-, 21-acetate (8CI) (11β,16β)-21-(Acetyloxy)-11-hydroxy-2′-methyl-5’H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione 2H-Naphth[2′,1′:4,5]indeno[1,2-d]oxazole, 5’H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione deriv. Azacort Azacortinol Calcort DL 458IT Deflan Optical Rotatory Power +62.3 ° Conc: 0.5 g/100mL; Solv: chloroform (67-66-3); … Continue reading

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PRIDOPIDINE OXIDE

Pridopidine OXIDE Example 5 – Preparation Of Compound 5 (4-(3-(methylsulfonyl)phenyl)-l-propylpiperidine 1-oxide) Pridopidine (50.0g, 178mmol, leq) was dissolved in methanol (250mL) and 33% hydrogen peroxide (20mL, 213mmol, 1.2eq). The reaction mixture was heated and kept at 40°C for 20h. The reaction … Continue reading

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SETILEUTON, MK 0633

MK 0633, SETILEUTON (-)-enantiomer 910656-27-8 CAS free form MW 463.3817, C22 H17 F4 N3 O4 FREE FORM Tosylate cas 1137737-87-1 2H-1-Benzopyran-2-one, 4-(4-fluorophenyl)-7-[[[5-[(1S)-1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl]amino]methyl]- 4-(4-Fluorophenyl)-7-[[[5-[(1S)-1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl]amino]methyl]-2H-1-benzopyran-2-one WO2006099735A1 Inventors Thiadiazole substituted coumarin derivatives and their use as leukotriene biosynthesis inhibitor WO 2006099735 A1Marc Blouin, … Continue reading

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Highly chemoselective reduction of nitroarenes over non-noble metal nickel-molybdenum oxide catalysts

Originally posted on ORGANIC CHEMISTRY SELECT: Highly chemoselective reduction of nitroarenes over non-noble metal nickel-molybdenum oxide catalysts Green Chem., 2017, 19,809-815 DOI: 10.1039/C6GC03141B, Paper Haigen Huang, Xueguang Wang, Xu Li, Chenju Chen, Xiujing Zou, Weizhong Ding, Xionggang Lu A non-noble … Continue reading

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Asymmetric synthesis of (S)-phenylacetylcarbinol – closing a gap in C–C bond formation

Originally posted on Green Chemistry International: Fig. 3 Stereoselectivities of the new ApPDC-variants for the synthesis of (S)-PAC. The different variants were tested as wet cells, crude cell extracts, and purified enzymes. Reaction conditions: wet cells – 20 mM benzaldehyde; … Continue reading

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Endogenous water-triggered and ultrasound accelerated synthesis of 1,5-disubstituted tetrazoles via a solvent and catalyst-free Ugi-azide reaction

Originally posted on ORGANIC CHEMISTRY SELECT: ? Endogenous water-triggered and ultrasound accelerated synthesis of 1,5-disubstituted tetrazoles via a solvent and catalyst-free Ugi-azide reaction Green Chem., 2017, Advance Article DOI: 10.1039/C6GC03324E, Communication Shrikant G. Pharande, Alma Rosa Corrales Escobosa, Rocio Gamez-Montano … Continue reading

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Pd/Cu-free Heck and Sonogashira cross-coupling reaction by Co nanoparticles immobilized on magnetic chitosan as reusable catalyst

Pd/Cu-free Heck and Sonogashira cross-coupling reaction by Co nanoparticles immobilized on magnetic chitosan as reusable catalyst Green Chem., 2017, Advance Article DOI: 10.1039/C6GC03377F, Paper Abdol R. Hajipour, Fatemeh Rezaei, Zahra Khorsandi Chitosan (CS) is a porous, self-standing, nanofibrillar microsphere that … Continue reading

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The Magic of Cubane!

  Cubane[1] Pentacyclo[4.2.0.02,5.03,8.04,7]octane CAS 277-10-1 Cubane (C8H8) is a synthetic hydrocarbon molecule that consists of eight carbon atoms arranged at the corners of a cube, with one hydrogen atom attached to each carbon atom. A solid crystalline substance, cubane is one of the Platonic hydrocarbons. It was first synthesized in 1964 by Philip Eaton, … Continue reading

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Curcumin: A Spice Against Alzheimer’s

Polymeric nanoparticles encapsulating curcumin improve memory and cognitive functions in a rat model of Alzheimer disease Curcumin: A Spice Against Alzheimer’s Read more Share this:

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A New Approach to Malaria Treatment?

A New Approach to Malaria Treatment? Halogenated natural alkaloids show herbicidal and antiplasmodial activity Read more Share this:

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