Category: ORGANIC CHEMISTRY

The Magic of Cubane!

  Cubane[1] Pentacyclo[4.2.0.02,5.03,8.04,7]octane CAS 277-10-1 Cubane (C8H8) is a synthetic hydrocarbon molecule that consists of eight carbon atoms arranged at the corners of a cube, with one hydrogen atom attached to each carbon atom. A solid crystalline substance, cubane is one of the Platonic hydrocarbons. It was first synthesized in 1964 by Philip Eaton, a professor of chemistry at the University of Chicago.[2] Before Eaton and Cole’s work, researchers believed that… Continue reading The Magic of Cubane!

Synthesis of Azadirachtin

Azadirachtin 11141-17-6  cas no Azadirachtin, a chemical compound belonging to the limonoid group, is asecondary metabolite present in neem seeds. It is a highly oxidizedtetranortriterpenoid which boasts a plethora of oxygen functionality, comprising an enol ether, acetal, hemiacetal, and tetra-substituted oxirane as well as a variety of carboxylic esters. This compound is a tetraterpenoid characteristic of the Meliaceae family but particularly from the Neem tree (A. indica), indigenous to… Continue reading Synthesis of Azadirachtin

Whisky lactone

Whisky Lactone Whisky lactone, also known as β-methyl-γ-octalactone or quercus lactone (from the Latin for oak treeQuercus alba), is a flavouring found in American bourbon whiskies, and is also found in all types of oak. The flavour gets into the whisky when it’s matured in oak barrels. The pure molecule has a fierce, strong, and sweet smell… Continue reading Whisky lactone

Green N-Methylation of Electron Deficient Pyrroles with Dimethylcarbonate

The N-methylation of electron-deficient pyrroles was affected using dimethyl carbonate in the presence of DMF and catalytic DABCO. This alkylation methodology has proven useful for the alkylation of a variety of pyrroles in 72−98% yields and is considered to be greenchemistry relative to the more common use of methyl halides or dimethyl sulfate. Michael L. Laurila , Nicholas A.… Continue reading Green N-Methylation of Electron Deficient Pyrroles with Dimethylcarbonate

Article On Alternative Solvents:  Shades of Green

The use of alternative reaction solvents is reviewed in terms of life cycle. Supercritical CO2, ionic liquids, fluorous solvents, water, and renewable organics are compared on the basis of their solvency, ease of use, reusability, health and safety, environmental impact, and economic cost. James H. Clark * and Stewart J. Tavener Green Chemistry Centre, Department of Chemistry, University… Continue reading Article On Alternative Solvents:  Shades of Green

Axial-to-central chirality transfer in cyclization processes

Axial-to-central chirality transfer in cyclization processes Substrates, bearing axial chirality, can cyclize intra- or inter-molecularly with concomitant transfer of axial-to-central chirality to produce at least one stereocenter. In order to satisfy a strict definition of axial-to-central chirality transfer, the initial axial chirality must be lost during the cyclization process. Highly functionalized enantiopure carbocycles and heterocycles… Continue reading Axial-to-central chirality transfer in cyclization processes

Chemical conversion of biomass-derived hexose sugars to levulinic acid over sulfonic acid-functionalized graphene oxide catalysts

Green Chem., 2013, 15,2935-2943 DOI: 10.1039/C3GC40353J, Paper Pravin P. Upare, Ji-Woong Yoon, Mi Yeon Kim, Hyo-Yoon Kang, Dong Won Hwang, Young Kyu Hwang, Harold H. Kung, Jong-San Chang Sulfonated graphene oxide (GO-SO3H) catalyst selectively decomposes glucose to levulinic acid (LA) with excellent yield (around 78%). Chemical conversion of biomass-derived hexose sugars to levulinic acid over sulfonic… Continue reading Chemical conversion of biomass-derived hexose sugars to levulinic acid over sulfonic acid-functionalized graphene oxide catalysts

ONE LAKH PLUS VIEWS ON ALL MY BLOGS-DR ANTHONY CRASTO

DR ANTHONY MELVIN CRASTO Ph.D WORLDDRUGTRACKER ANNOUNCING ONE LAKH PLUS VIEWS ON ALL BLOGS- DR ANTHONY CRASTO Eurekamoments in Organic Chemistry NEW DRUG APPROVALS WORLD DRUG TRACKER Green Chemistry International drug regulatory affairs international ORGANIC SPECTROSCOPY INTERNATIONAL ORGANIC SYNTHESIS INTERNATIONAL ALL ABOUT DRUGS ORGANIC CHEMISTRY INTERNATIONAL Drug Scaleup and Manufacturing International SEE ALSO Organic Chemistry by… Continue reading ONE LAKH PLUS VIEWS ON ALL MY BLOGS-DR ANTHONY CRASTO

NANOPUTIANS

Systematic name 2-(4-{2-[3,5-bis(pent-1-yn-1-yl)phenyl]ethynyl}-2,5-bis(3,3-dimethylbut-1-yn-1-yl)phenyl)-1,3-dioxolane Other names 1,3-dioxolane, 2-[2,5-bis(3,3-dimethyl-1-butyn-1-yl)-4-[2-(3,5-di-1-pentyn-1-ylphenyl)ethynyl]phenyl] NanoKid NanoPutian 618904-86-2  cas NanoPutians are a series of organic molecules whose structural formulae resemble human forms.[1] James Tour et al. (Rice University) designed and synthesized these compounds in 2003 as a part of a sequence of chemical education for young students.[2] The compounds consist of two benzene rings connected via a few carbon atoms as the body,… Continue reading NANOPUTIANS