Cu(II)-catalyzed decarboxylative acylation of acyl C–H of formamides with -oxocarboxylic acids leading to -ketoamides |
Dengke Li,a Min Wang,*a Jie Liu,a Qiong Zhaoa and Lei Wang*ab |
Chem. Commun., 2013, 49(35), 3640-3642 |
http://pubs.rsc.org/en/content/articlelanding/2013/cc/c3cc41188eDOI: 10.1039/C3CC41188E |
CuBr2-catalyzed decarboxylative acylation of the acyl C–H of N-monosubstituted and N,N-disubstituted formamides with α-oxocarboxylic acids leading to α-ketoamides was developed, which generated the corresponding products in good yields.
Corresponding authors
a
Department of Chemistry, Huaibei Normal University, Huaibei, P. R. China
E-mail: leiwang@chnu.edu.cn ;
Fax: +86-561-309-0518 ;
Tel: +86-561-380-2069
E-mail: leiwang@chnu.edu.cn ;
Fax: +86-561-309-0518 ;
Tel: +86-561-380-2069
b
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, P. R. China