Monthly Archives: January 2013

(Z)-5-tetradecen-1-ol, Potential female sex attractant

Follow my blog with Bloglovin (Z)-5-Tetradecen-1-ol, mw  212.37,   formula  C14H20O   CAS   40642-42-0 Odorant receptors, present on nasal sensory neurons, perceive volatile compounds and regulate animal behavior such as reproduction. The nature of the ligands interacting with these receptors is, however, … Continue reading

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AT13148, Drug Blocks Multiple Cancer Causes

AT13148 AT13148 is a multi-AGC kinase, ATP-competitive inhibitor, identified utilizing high-throughput X-ray crystallography and fragment-based lead discovery techniques. AT13148 caused substantial blockade of AKT, p70S6K, PKA, ROCK and SGK substrate phosphorylation and induction of apoptosis in both a concentration and … Continue reading

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Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2’-Deoxy and 2’,3’-Dideoxynucleosides

Continuous Flow Photochemistry for the Rapid and Selective Synthesis of 2’-Deoxy and 2’,3’-Dideoxynucleosides http://www.publish.csiro.au/nid/51/paper/CH12426.htm Bo Shen and Timothy F. Jamison Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. Australian Journal of Chemistry – http://dx.doi.org/10.1071/CH12426 Published online: 19 November … Continue reading

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Bedaquiline(Sirturo, TMC207 or R207910) FDA approves 1st new tuberculosis drug in 40 years

  (1R,2S)-1-(6-Bromo-2-methoxy-3-quinolyl)-4-dimethylamino-2-(1-naphthyl)-1-phenyl-butan-2-ol, cas no 654653-81-3 Bedaquiline FDA approves 1st new tuberculosis drug in 40 years The Food and Drug Administration on Monday approved a Johnson & Johnson tuberculosis drug that is the first new medicine to fight the deadly infection … Continue reading

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LM11A-31, New drug can help paralyzed people walk again

  LM11A-31, C12 H25 N3 O2, Pentanamide, 2-amino-3-methyl-N–[2-(4-morpholinyl)ethyl]– WO 2010102212 TO LONGO FRANK, PUB 10.09.2010 THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL PATENT LINK    http://patentscope.wipo.int/search/en/WO2010102212 Scientists have developed a pill which they claim could help paralyzed people walk … Continue reading

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Synthesis of vitamin E

The α-tocopherol form of vitamin E Vitamin E refers to a group of eight fat-soluble compounds that include both tocopherolsand tocotrienols.[1] There are many different forms of vitamin E, of which γ-tocopherol is the most common in the North American diet.[2] γ-Tocopherol can be found in corn … Continue reading

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Facile Synthesis of Benzaldehyde-Functionalized Ionic Liquids and Their Flexible Functional Group Transformations

Facile Synthesis of Benzaldehyde-Functionalized Ionic Liquids and Their Flexible Functional Group Transformations http://www.hindawi.com/journals/oci/2012/208128/ Organic Chemistry International Volume 2012 (2012), Article ID 208128, 5 pages doi:10.1155/2012/208128 Qiang Huang and Baozhong Zheng Department of Materials Science and Engineering, Yunnan University, Kunming 650091, China Three benzaldehyde-functionalized ionic … Continue reading

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Transition Metal Ions as Efficient Catalysts for Facile Ortho-Formylation of Phenols under Vilsmeier–Haack Conditions

organic chemistry international, v 2012 Volume 2012 (2012), doi:10.1155/2012/289023 Transition Metal Ions as Efficient Catalysts for Facile Ortho-Formylation of Phenols under Vilsmeier–Haack Conditions F. Aneesa,1 K. C. Rajanna,2 Y. Arun Kumar,1 and M. Arifuddin3 1Department of Chemistry, Muffakham Jah College of Engineering and Technology, Mount … Continue reading

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The Formal Total Synthesis of FR252921 – An Immunosuppressant

The Formal Total Synthesis of FR252921 – An Immunosuppressant European Journal of Organic Chemistry Volume 2013, Issue 2, pages 376–388, January 2013 J. S. Yadav and Sandip Sengupta Article first published online: 15 NOV 2012 | DOI: 10.1002/ejoc.201201097 http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201201097/abstract   … Continue reading

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CES as an Efficient Natural Catalyst for Syn of Schiff Bases under Solvent-Free Conditions: An Innovative Green Approach

CES (calcined eggshell) Organic Chemistry International, Volume 2012 (2012), doi:10.1155/2012/153159 CES as an Efficient Natural Catalyst for Synthesis of Schiff Bases under Solvent-Free Conditions: An Innovative Green Approach Suresh Patil, S. D. Jadhav, and S. K. Shinde Organic Research Laboratory, Department of … Continue reading

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