Immobilized Catalysts for Hydroformylation Reactions: A Versatile Tool for Aldehyde Synthesis (pages 6309–6320) Ângela C. B. Neves, Mário J. F. Calvete, Teresa M. V. D. Pinho e Melo and Mariette M. Pereira Article first published online: 18 SEP 2012 | DOI: 10.1002/ejoc.201200709 The most relevant results relating to the development and use of catalysts supported… Continue reading Immobilized Catalysts for Hydroformylation Reactions: A Versatile Tool for Aldehyde Synthesis
Month: October 2012
Luche reduction
Luche reduction is the selective organic reduction of ketones to alcohols with lanthanoid chlorides such as cerium(III chloride andsodium borohydride. The Luche reduction can be conducted chemoselectively toward ketone in the presence of aldehyde or toward α,β-unsaturated ketone in the presence of non-conjugated ketone.1,2,,3 An enone forms an allyl alcohol in a 1,2-addition. Competing conjugate 1,4-addition is suppressed. The solvent is an alcohol such asmethanol or ethanol. The selectivity can be explained in terms of HSAB theory: carbonyl groups require hard nucleophiles for 1,2-addition. The… Continue reading Luche reduction
Process for the preparation of an HIV integrase inhibitor, WO-2012138670, Gilead Sciences Inc
Process for the preparation of an HIV integrase inhibitor, WO-2012138670, Gilead sciences inc Li, Wenjie; De Croos, Philomen; Fandrick, Keith, R.; Gao, Joe, Ju; Haddad, Nizar; Lu, Zhi-Hui; Qu, Bo; Rodriguez, Sonia; Senanayake, Chris, H.; Zhang, Yongda; Tang, Wenjun, PUB 11 OCT 2012, Drug BI-224436 ((Tentative)) GILEAD, under license from BOERINGER ING, is developing… Continue reading Process for the preparation of an HIV integrase inhibitor, WO-2012138670, Gilead Sciences Inc
Dehydration of Carbohydrates to 5-Hydroxymethylfurfural in Ionic Liquids Catalyzed by Hexachlorotriphosphazene
Dehydration of Carbohydrates to 5-Hydroxymethylfurfural in Ionic Liquids Catalyzed by Hexachlorotriphosphazene (pages 2079–2084)http://onlinelibrary.wiley.com/doi/10.1002/cjoc.201200691/abstractJinliang Song, Binbin Zhang, Jinghua Shi, Jun Ma, Guanying Yang and Buxing Han Article first published online: 25 SEP 2012 | DOI: 10.1002/cjoc.201200691 Highly efficient synthesis of 5-hydroxymethylfurfural (HMF) by dehydration of carbohydrates was catalyzed by hexachlorotriphosphazene (N3P3Cl6) in ionic liquids. Development of… Continue reading Dehydration of Carbohydrates to 5-Hydroxymethylfurfural in Ionic Liquids Catalyzed by Hexachlorotriphosphazene
Starch as a replacement for urea-formaldehyde in medium density fibreboard
Thermoplastic starch can be used to bind wood flour to produce a fibreboards which are mouldable, recyclable and ultimately compostable. Medium density fibreboard (MDF) is a ubiquitous product formed from wood flour and a formaldehyde-based resin. The use of the latter component causes some health and environmental concerns and its use is restricted. The… Continue reading Starch as a replacement for urea-formaldehyde in medium density fibreboard